Created
August 14, 2023 16:10
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from scipy.stats import norm | |
def detectable_difference(alpha, power, proportion, n_positives): | |
""" | |
Calculate the detectable difference in proportions for a given sample size, power, significance level, and proportion. | |
Parameters: | |
alpha: Significance level | |
power: Desired power of the test | |
proportion: Proportion in the control group (e.g., existing provider detection rate) | |
n_positives: Number of positive examples | |
Returns: | |
detectable_difference: Detectable difference in proportions | |
""" | |
z_alpha = norm.ppf(1 - alpha / 2) | |
z_power = norm.ppf(power) | |
p1 = proportion | |
p2 = p1 # Assuming null hypothesis that the proportions are equal | |
p_bar = (p1 + p2) / 2 | |
q_bar = 1 - p_bar | |
n1 = n_positives | |
n2 = n_positives # Assuming equal sample sizes | |
delta = z_alpha * ((p_bar * q_bar * (1 / n1 + 1 / n2)) ** 0.5) + z_power * ( | |
(p1 * (1 - p1) / n1 + p2 * (1 - p2) / n2) ** 0.5 | |
) | |
detectable_difference = delta / (1 + (p1 * (1 - p1) / p2 / (1 - p2)) ** 0.5) | |
return detectable_difference | |
# Given parameters | |
alpha = 0.05 | |
power = 0.80 | |
provider_detection_rate = 0.8 | |
total_images = 2000 | |
occult_femoral_fracture_incidence = 0.03 | |
positive_cases = int(total_images * occult_femoral_fracture_incidence) | |
# Calculate detectable difference | |
difference = detectable_difference( | |
alpha, power, provider_detection_rate, positive_cases | |
) | |
print( | |
f"The detectable difference in detection rate is approximately {difference * 100:.2f}%" | |
) |
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