Simplest way to generate PDF with Weasyprint (http://weasyprint.readthedocs.io) and a Web Framework. I use Django, but it can be surely used with others + jinja for templating. First, render an HTML page as string, then generate the pdf and serve it as response.

gistfile1.txt

from weasyprint import HTML
        
        response = HttpResponse(content_type='application/pdf')
        response['Content-Disposition'] = 'attachment; filename="your_pdf.pdf"'

        html_out = str(render(request,"mock_page.html",locals()))
        html_out = html_out.replace('Content-Type: text/html; charset=utf-8','')
        # base_url is used to locate the CSS file
        HTML(string=html_out,base_url = request.build_absolute_uri()).write_pdf(response)
        return response